Listings of seminars and department events for the week of February 6 to February 10, 2012
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The Actin Cytoskeleton Controls B Cell Receptor Dynamics and Signalling
Dr. Bebhinn Treanor
Department of Biological Sciences
University of Toronto

1:30 pm, February 3
Room 1527, Hill Wing
Hospital for Sick Children

Host: Dr. Sergio Grinstein
Program in Cell Biology Seminar Series, Hospital for Sick Children

Beyond Dreams: How Twitches during REM Sleep Contribute to Sensorimotor Development
Dr. Mark Blumberg
University of Iowa, Department of Psychology

2:00 pm, February 3
Ramsay Wright Building, Room 432

Host: Peter Schwarz
CSB Seminar

Adhesion molecules governing the entry of immune cells into the CNS
Alexandre Prat, MD, PhD, FRCPc
Center of Excellence in Neuromics
Head of Neuroscience Research, CHUM-Université de Montrèal
Professor of Medicine and Immunology Université de Montrèal

11:10 am, February 6
Medical Sciences Building Room 2172

Host: Dr. Jennifer Gommerman
Department of Immunology Easton Seminar Series

Investigation of non-translational strategies to enhance recombinant human bone morphogenetic protein-2 production in mammalian cell culture systems
Aileen Zhou
Ph.D. Candidate;
Oral and Maxillofacial Surgery, Faculty of Dentistry,

11:30 am, February 6
Room #237, Fitzgerald Building

Supervisors: Dr. Cameron Clokie and Dr. Sean Peel
CIHR Group in Matrix Dynamics seminar


Probing cancer cell signaling by NMR: structure, interaction, and enzymatic kinetics of small GTPases
Dr. Mitsu Ikura
Ontario Cancer Institute and
Department of Medical Biophysics, University of Toronto

1:00 pm, February 6
Room 1250 Burton Wing, The Hospital for Sick Children

Host: Dr. P. Lynne Howell
Molecular Structure and Function Seminar Series

The role of LKB1/Par4 in epithelial cell polarity and morphogenesis: a chemical-genetic mouse model and cancer ex vivo
Dr. Bryan Lo
Research Fellow, Dept. of Research Oncology, Genentech, San Francisco, CA

2:00 pm, February 6
610 Unviversity Avenue, PMH Auditorium, 6th Floor, Room 604

Host: Dr. Senthil Muthuswamy
OCI Seminar

Exploring ’Pain Space
Dr. Michael W. Salter MD PhD FRSC
HHMI International Scholar Anne and Max Tanenbaum Chair in Molecular Medicine Canada Research Chair in Neuroplasticity and Pain (Tier I) Associate Chief, Science Strategy, Senior Scientist and Head, Program in Neurosciences & Mental Health Hospital for Sick Children and Professor of Physiology, University of Toronto

4:00 pm, February 6
Medical Sciences Building Room 2172

Host: Dr. Michael Ohh
Laboratory Medicine & Pathobiology Seminar Series

Fertility treatments for men with CF
Dr. Keith Jarvi
Chief, Division of Urology Mount Sinai Hospital

5:00 pm, February 6
Room 7704, Atrium (Sickkids)

Cystic Fibrosis Seminar

Leukocyte trafficking and autoimmunity: How do we study this in humans and what is the future for trafficking inhibitors as disease-modifying therapies?
Alexandre Prat, MD, PhD, FRCPc
Center of Excellence in Neuromics
Head of Neuroscience Research, CHUM-Université de Montrèal
Professor of Medicine and Immunology Université de Montrèal

5:00 pm, February 6
Medical Sciences Building Room 7231

Host: Dr. Jennifer Gommerman
Panel Discussions in Human Immunology

Potential role of heterologous immunity in experiments of man and nature
Dr. Simon Mallal
Director, Institute for Immunology & Infectious Diseases, Murdoch University
Professor and Executive Director, Centre for Clinical Immunology & Biomedical Statistics,
Royal Perth Hospital and Murdoch University, Perth, Australia

12:00 pm, February 7
Medical Sciences Building Room 2172

Host: Dr. Michael Ratcliffe
Department of Immunology Seminar

Hunting suppressor mutations in S. cerevisiae using high-throughput sequencing
Takafumi Yamaguchi
Graduate Student

2:00 pm, February 7
Red Seminar Room, Donnelly CCBR

Supervisor: Dr. F. Roth
Department of Molecular Genetics

Proteomic profiling of the planarian S. mediterranea by mass spectrometry and elucidation of the planarian mucous proteome
Donald Bocchinfuso
Graduate Student

2:30 pm, February 7
Red Seminar Room, Donnelly CCBR

Supervisor: Dr. M. Moran
Department of Molecular Genetics

Investigating the regulation of GLI transcription factors in pancreatic cancer
Wen Qi Yin
Graduate Student

2:00 pm, February 7
18th Floor Auditorium, Mt. Sinai Hospital

Supervisor: Dr. C.C. Hui
Department of Molecular Genetics

Investigating Differential Expression of MicroRNAs in Breast Cancer Subtypes
Dylan Ehman
Graduate Student

2:30 pm, February 7
18th Floor Auditorium, Mt. Sinai Hospital

Supervisor: Dr. I. Andrulis
Department of Molecular Genetics

EGFR, a driving pathway of chronic kidney disease progression
Dr. Fabiola Terzi
Hopital Necker - Enfants Malades Paris, France

12:00 pm, February 8
Mount Sinai Hospital, 60 Murray St. Level 3 Conference Rooms L3-201-202-203

Host: Dr. Helen McNeill
Samuel Lunenfeld Research Institute Seminar Series

Characterization of the Alr domain of the Saccharomyces cerevisiae magnesium channel Alr1
Natasha Kruglyak
Graduate Student, Ph.D. Program

4:00 pm, February 8
Medical Sciences Building Room 2172

Supervisor: Dr. Emil F. Pai, Committee: Drs. Christine Bear and Gil Prive
Department of Biochemistry Graduate Student Seminar Series

Understanding UGGT?s mechanism of recognition and catalysis
Jesse Hackett
Graduate Student, M.Sc. Program

4:00 pm, February 8
Medical Sciences Building Room 2172

Supervisor: Dr. James Rini
Committee members: Dr David Williams, Dr. Lynne Howell
Department of Biochemistry Graduate Student Seminar Series

Bacterial Surface Lipoproteins - Premiere Targets for Antimicrobial Therapeutics
Trevor Moraes, Ph.D.
Assistant Professor
Department of Biochemistry, University of Toronto

4:00 pm, February 8
Room 103, Fitzgerald Building

Department of Pharmacology & Toxicology Seminar

Modulating tissue inflammation and autoimmunity by inducing T cell exhaustion: role of the Tim-3 signaling pathway
Dr. Manu Rangachari
Center for Neurologic Diseases
Brigham & Women's Hospital, Harvard Medical School

4:00 pm, February 8
Medical Sciences Building Room 7231

Host: Dr. Mario Ostrowski
Department of Immunology Seminar

Regulation of cell death and vascular tube formation in C. elegans by the CCM genes
Dr. Brent Derry
Hospital for Sick Children

12:00 pm, February 9
Ryerson University ENG102 (ENG is at the corner of Church and Gould Sts)

Host: Roberto Botelho
Dept. Chemistry and Biology Ryerson University

Platelet Secretion: Molecules to Disease and Back
Dr. Sidney Whiteheart
Department of Molecular and Cellular Biochemistry, University of Kentucky

1:30 pm, February 10
Room 1527, Hill Wing Hospital for Sick Children

Host: Dr. Walter Kahr
Program in Cell Biology Seminar Series, Hospital for Sick Children

Predicting Genome-Wide Protein-Protein Interactions and Identification of Novel Gene Functions in Eukaryotes
Dr. Ashkan Golshani
Carleton University, Department of Biology

2:00 pm, February 10
Ramsay Wright Building, Room 432

Host: Dr. Mounir AbouHaidar
CSB Seminar

Adolescence as a "sensitive period" to the effects of social stressors: Effects on the HPA axis and on cognitive function
Cheryl McCormick, Ph.D.
Canada Research Chair in Behavioural Science, Brock University

4:00 pm, February 10
Room # 560A, Ground Floor, Sidney Smith Hall, 100 St. George Street

Brain and Behaviour Seminar Spring Series